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The Effects of Intermittent Fasting on Human and Animal Health

I can see that you are using this article to try to bring people in and eventually sell them something. The way you are approaching it wont work-unless you really think people are going to read 10, words of science crap instead of just closing your site and going elsewhere.

While it may seem like jargon to you, it is the preferred lexicon for scholarly publications. Do NOT presume their level of education. I once listened to an Immunology professor at a University complain that the only articles he could understand in Science the journal were the ones on Immunology.

Trust me; if you were to pick up and try to read a scholarly academic article outside of your field, you would react the way Jeff is reacting. Oh dear Jeff, you have clearly shown that this level of academia is lost on you. This is an excellent review of the available literature, written by a highly educated person.

This is an extremely disrespectful comment that shows your lack of intelligence. Think things through before you comment in future. It is Your comment that is extremely disrespectful comment and shows a lack of intelligence and knowledge of how many different styles there are in the world. I have an MS in Microbiology and have been employed as a programmer and technical writer for over 25 years. Both Jeff and Notjeff seriously? Notjeff is sadly also correct. However, Audience is Everything.

If you want this information to be read and understood by people who are not your thesis committee or people with an MD or PhD in your field, you need to re-write it. This study confirms much of the anecdotal evidence that I had already heard about the possible long-term effects of intermittent fasting.

Interesting timing of this post as I was just talking with a co-worker about the benefits of intermittent fasting and the general practice of fasting.

Although it has been a while many years since I have practiced fasting, it is a ritual that I have studied and used its healthy benefits in the past. I have used short fasts of less than 36 hours and longer fasts of 7 days for personal research,purposes and practice. After having lived several years in an unhealthy way, I have re-tooled my lifestyle into a sustainable healthy way of living and have lost 55 pounds in the past year.

The subject of intermittent fasting came up as I believe that I will begin a regular practice of IF as a part of this lifestyle. I am looking forward the time when I can read your complete work as I have only scanned it this morning. Thanks for sharing your work with me. Thank you for sharing your research. The popular models of IF being 5: Do you have any results on their benefits from your research? I need to leave a quick comment just as I started reading The best and biggest recource base for the IF is by far Martin Berkhan, and his website leangains.

Now back to the reading…. It is a great summary and I do appreciate your work on this. Thanks for sharing this. It seems like most of the research in this area has been done on type two Diabetics. Ori may in fact be the first well-known proponent of IF and Warrior Diet should be recognized as one of original mainstream publications advocating IF for general health and physique improvements….

I spend much of my time researching information on fasting from peer reviewed journals through my university. I find the health benefits of IF, especially autophagy, are profound but tend to be poorly understood.

I have the article you posted. What do you know about this topic? Lots of writing but I was conflicted.. You talked in the beginning about this being your baby.. You made it sound like you had stumbled on some gold nuggets of previously unknown information.

Nice resource of information overall but I still fail to understand why so many people regard IF as some unique idea or think of it as a new way to solve an old problem. I tried it for a full year before realizing that my results were identical to when I ate 6 meals a day for a decade. Is it staving off disease in me a little longer and giving me a future benefit in that respect? Possibly but not conclusively. It matters little and this just seems to justify that. Eat 6 meals if you like or eat 1 or 2.

I can see great benefit in people linking to the article as a place to find many important studies on fasting. Most appreciate the hard work, and you choosing to publish this free for all to read and benefit after the hours of work. Will put several links up to it. It is true that junk food can totally screw up any health benefits of IF and the people that bash it did just that, or did unhealthy low carb or too low calorie or had lots of stress in other areas of life.

IF can also backfire if done to extreme. I mean come on. Thank you for all the work of putting it together! From perspective of 1.

Mood and energy 2. Long-term health and longevity 3. Physical and mental performance. All other things being equal, according to current data, should someone training two or three times a week fast once a week for the whole day or daily for about hours? Also, assuming the three days workout regimen Mon, Wed, Fri or two days workout regimen Mon and Fri what would be the best day to fast to get most of the benefits and sacrifice as little anabolism as possible?

Thank you for sharing it! Is there any scientific evidence to support the answer to this question? What of the following types of fasting should one do if he or she is not interested in weight loss but rather muscle gain , but is very interested in all other health benefits fasting might provide and specifically in the benefit below related to glomerulosclerosis as this one can be life-saving!

Intermittent fasting daily 1. Alternate day fasting 2. Rats fed on alternate days showed preserved kidney function as demonstrated by preserved glomerular filtration rate and renal plasma flow, compared to rats fed ad libitum. Effect of long-term, alternate day feeding on renal function in aging conscious rats. Although scientific in its approach, quite accessible to the rest of us to understand and assimilate. I can usually go to somewhere between 2 -4 pm.

But should I push it too long — I often do! What is causing it?! The symptoms you describe are associated with detoxing. You say the better your diet the less you experience them. The quality of your food matters, as the more toxins your body has to eliminate the more symptoms you will feel during your food-free periods. You should be able to push through these symptoms and stretch the length of time without food. Disregard this comment, all.

It seems like the carb reduction in paleo is helping. Maybe try being more strict with carb intake, 20g daily. I certainly appreciate a scientific paper on weight loss versus the advertisement-laced, fad based articles. I have read articles that state while research shows benefits for male subjects rodent and human alike , that longer periods of fasting were detrimental for females. I came across this thesis while researching for an article I am writing about IF for women specifically.

I have been practicing IF for a few years and despite many mishaps have finally hit a sweet spot with it. However, as you said have struggled to find reliable research, or in fact anything written on the subject at all. However, this is what I have found so far:. Already lost 28 lbs and broke all my personal best in the major lifts. Thank you for sharing your hard work. Great read Bojan, thank you for posting it online.

I especially liked the section regarding the Ramadan fast. And congratulations on your MD! Oh, my blood work looks incredible as well, with my total cholesterol in the s despite very high HDL and my triglycerides in the mid 50s.

Your research changes lives. This was incredibly well written, fascinating and informative. That day has finally come, it seems my fear of disappointment was just stopping me from looking a little harder. S Ramachandran, Dawkins and the Lancet Journal. I met a trainer who has a giant of a sculpted body. He told me something about slingshot training which was based on eating and fasting cycles. He said the body releases growth hormones when we fast.

Now it makes heck of a sense. Also, while fasting during Ramadan is mandatory, it is encouraged among Muslims to fast every Monday and Thursday. Very few people do it however. Like most good things in life. Fasting is prescribed to you as it was prescribed to those before you, that ye may learn self-restraint.

Thank you so much for sharing. I have been studying fasting for years on my own body as well as teaching it to others. I hope you write a book some day. I really appreciate not having to immerse myself in a stack of papers to understand some of the real science beyond IF. Just studies in rodents by now. With increased ketones due to short period fasting and Preventing the loss of non fat mass.

Can you advise a optimal period in hours of fasting followed by hours not fasting? Also on none fasting days. Would a ketogenic diet play some role in pre and post fast to minimise shock to the body and bring ketone levels up before a total nutritional cut off?

And any thoughts on carb loading or cheat days relating to IF? Why have you not had your work published in a peer reviewed journal? I find that highly suspicious. All that sounds great… but for a sec. I am from Greece and from family of building constructors. Those people were strong, lean, with stamina, poor, happy and optimistic. Now we are sick all the time, unsatisfied and with all my respect to the author work, with all that scientific data, — we forgetting that not only the quran reinforce fasting but the christianity too, vigorously i must say, — actually we exploring the proven results of fasting mechanism, without the way to reinforce the fundamental mentality of how to decide to live frugal.

Just a thought for further research: If so, why not settle on one unified term? If not, why are they used interchangeably throughout the article? Intermittent Fasting is the general classification covering all forms of short regular fasting, Alternate Day Fasting is a specific form of Intermittent Fasting where food is only eaten every second day.

Thank you for sharing your work. Intermittent fasting seems to be a generally safe and effective regime; your year-long efforts help reveal the scientific underpinnings.

I was a half-assed pescatarian for many years. I went full vegan in March Going vegan was hard, especially the beginning. In March I was around My partner gets home late, loves to cook and thinks nothing of eating a gigantic steak and full meal at 11pm. It was a tough change for me. Now, I limit my food to window of time. Mid-to-late morning thru till around 6pm at the very latest. It seems to me like I almost need those occasional times to re-jumpstart the downward trend.

I swim for 20 minutes a day. I think dropping your body temp for a while also is good for kick-starting your body energy. I love to dance and dance around our condo all the time. I work from home. I realized that I was doing some kind of intermittent fasting and it sure seems to line up with my experience. I feel euphoric often. I feel so dang healthy I want to shout it from the rooftops! Now, I eat for nutrition. I listen to my body more. I feel like a different person.

I feel clean and wonderful inside! Sorry, I meant so say I went Vegan in March My weight loss has been about a month journey. Is there a spot where I can get more basic how to details on the types of IF…and also figure our which is best more weight loss.

I am not obese…just modern day over weight. Mind blown, thank you so incredibly much. I only take about 3 grams. And one small lime, which has about 5mL of juice. Congratulations on acquiring your MD. I will hopefully be following in your footsteps when I graduate in Thank you for the Great work you have done!

Its a appreciated as much as I appreciat my kids! Thank you so much for sharing your research and information. It is refreshing to know that someone is giving the information to anyone that wants to access it for free.

Superb review, thank you so much for sharing. I am an undergraduate studying nutrition and I am currently writing my dissertation on time to exhaustion in male subjects during intermittent fasting.

The collation of literature here has helped me no end. Thank you so much again for sharing and congratulations on achieving your MD!

I added this to my website, which is all about intermittent fasting information, to share with others. Very nice review, Sir; very useful to me. The only result of your paper is the last sentenace: Very little in the morning, a glass of fresh juice; very little in the evening, a few nuts or some cheese. My proper meal consists of good protein and fat, a decent serving of veg and some fruit — and never forget your dark chocolate!

No wheat, no added sugar — but also no actual rules. So does that count as IF? Is there any science on that model? I stopped weighing myself many years ago. I also need less sleep. That could be an angle for a study. Did they check that with the rodents? Also, please let all those non science-reading people on Facebook know that eating non-stop is bad! Thank you Bojan, the reeding was easy going and yet technical and informative.

I appreciate your effort and thank you for motivating me and the rest of the readers into opening up to new possibilities whilst feeling confidente of the path we are taking. Keep it up, people will follow. I enjoyed reading your articles. This is truly a great read for me.

I have bookmarked it and I am looking forward to reading new articles. Keep up the good work. If fact some of the responses you received are the type of Knee Jerk reactions I see all the time.

I loved the read! I know this is old, however I have no PhD, no analytical writing skills, or proper grammer. And I understood everything as it was ment to be understood. Proves that IF has many more benefits than just weight loss. However, have you seen any studies on continued ADF vs. Your email address will not be published. You may use these HTML tags and attributes: I am finally ready to go public. A quick background story… Why IF?

I got my MD and felt on top of the world. Now, grab a big cup or coffee and enjoy the read. Bengt Zöller, Staffan Lindeberg Examination: Mechanisms of calorie restriction and intermittent fasting. Potential adverse effects from fasting. May 22, at 7: June 6, at 5: May 22, at May 22, at 6: May 22, at 8: May 23, at May 23, at 7: January 3, at 8: July 6, at October 19, at 3: January 18, at 7: July 6, at 6: April 14, at 1: June 2, at 4: July 6, at 7: May 24, at John A Hill says: May 24, at 4: May 27, at 1: May 30, at 5: May 30, at 6: June 19, at 6: May 30, at 9: May 30, at May 30, at 4: May 30, at 7: June 1, at 7: June 2, at 1: June 4, at 2: June 6, at 4: June 8, at 5: June 11, at 4: June 18, at 1: June 23, at September 16, at April 10, at 7: February 25, at 8: March 28, at 4: July 10, at 5: June 19, at 4: July 14, at 2: July 14, at 9: July 19, at 7: July 30, at 3: August 11, at 9: August 9, at 9: August 11, at 7: August 22, at 4: September 7, at 7: September 25, at 1: September 29, at 5: October 12, at 1: October 28, at 4: November 4, at December 20, at 3: July 7, at 1: January 9, at 7: January 10, at January 12, at 1: February 2, at 9: February 4, at February 9, at 5: March 7, at 6: March 13, at 6: March 15, at 8: EQ, Primo -Strength Steroids: Test, Drol, Dbol, Tren and to a lesser extent: EQ, Drol and to a lesser extent: Winny, Halo, Var, Tren -Steroids with direct fat-burning properties: Halo, Methyltest -Mostly Anabolic Steroids: Test, Tren -Liver Toxic Steroids: Tren -Acts like an estrogen: Slin -Drugs for Strength: Finasteride - Fat Burners: Bromo -Stimulates LH release: Clomid, Nolva, GH -Drugs that increase red-blood cell count: Ok so now that you know what drugs do what, we can begin to discuss what properties a cycle should have.

From there we can begin to see how these drugs can be combined to form a? The idea behind the stack is to create a synergy between the drugs involved to give an effect that? These are cycles were all out mass is required. Here we give no consideration to fat gain, water gain or any of that stuff.

We are just looking to pack on as much muscle as possible don? To get all out mass, we need to attack our system from all angles. We need steroids that are highly androgenic and highly anabolic.

We need steroids that are known to pack on a lot of mass. In general, steroids that do not aromatize, do not activate the AR and do not pack on a lot of mass aren? For injectables we would rather have long acting esters than short ones, as the long acting esters tend to pool up in your blood and generally leave you with more hormone at any given point.

For orals we prefer those that either aromatize heavily, or cause an explosion of mass by similar estrogenic properties. The use of orals is mainly to kick off the mass cycle, gives you near instant results and puts your body in a good anabolic state when the long acting esters kick in. With all that said the best steroids for mass are: Advanced users can also use things like Insulin and GH. Realize that with the exception of Test, Tren and Anavar, no steroid has a direct impact on fat burning.

Even Test, Tren and Var have limited effects on fat burning. These steroids are going to help me loose fat.? Instead you should think of the steroids as muscle sparring.

All steroids listed above meet the first requirement; they will all help you retain muscle in a calorie deficient diet. However, if you are cutting you certainly do not want your steroids to be in the way either.

Some steroids drol actually make it harder to loose fat. Others can bloat you up so bad that even with a low body fat percentage, most of your definition can be lost. So what we need here is steroids that are more androgenic than anabolic. We need steroids that have direct fat burning properties and steroids that do not aromatize heavily.

If we do use a long acting ester, we would prefer to use one that doesn? But I can take a guess and you guys that do participate in sports can probably figure it out given my explanations. First lets looks at sports that require strength without increased mass. Any steroid that aromatizes heavily is not desirable here, as the extra water will certainly make you put on weight.

Your best drugs for this purpose would be: Halo, Winny, Var and GH. If you can afford a few extra pounds like in the offseason or what not , Tren would also be a good steroid.

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